When using fatty emulsions for a long time recommended to periodically perform a general analysis of blood and coagulation.
In patients with renal failure and the introduction of potassium phosphate should be performed with caution in order to prevent the development of hyperkalemia and hyperphosphatemia.
Additional quantities of electrolytes should be added to the drug testosterone suspension gains peripheral given clinical situations where it is necessary to determine their daily plasma concentration.
If a patient has lactic acidosis, insufficient oxygen supply and increased plasma osmolarity parenteral nutrition should be used with caution.
The fat content of peripheral SMOFKabiven® solution can lead to incorrect results of some laboratory tests (such as bilirubin, lactate dehydrogenase, hemoglobin oxygenation, hemoglobin) if blood samples were obtained prior to removal of fat from the circulation. In most patients, the blood in the vascular bed is freed from fat for 5-6 hours after the termination of his conduct.
Intravenous administration is accompanied by increased excretion amino micronutrients, particularly zinc and copper, with urine. This should be taken into account when adding trace elements in parenteral nutrition, especially if it will be a long time. It is necessary to take into account the amount of zinc, which is part of the peripheral .
Patients with impaired nutritional status beginning parenteral nutrition can result in some fluid retention, which in turn can contribute to the development of pulmonary edema and congestive heart failure, and reduce the concentration of potassium, phosphorus, magnesium and water soluble vitamins in the plasma. These events may occur within 24 – 48 hours after the start of parenteral nutrition. They can be avoided by starting parenteral nutrition gradually and carefully monitored and time to amend the amount of input of electrolytes, minerals, vitamins and fluids.
Testosterone suspension gains peripheral should not be administered concurrently with the blood in a single system due to the risk of psevdoagglyutinatsii.
Patients with hyperglycemia, insulin may be needed.
Overdose symptoms, relief measures in overdose
overload syndrome fat
Impaired ability to metabolize triglycerides can lead to “fat overload syndrome” which may be caused by an overdose of lipids. It is necessary to pay attention to possible signs of metabolic overload. Causes of impaired lipid metabolism may be genetic (individual metabolic changes), in addition to the fat metabolism may affect the present or previous condition. Hypertriglyceridemia and high fat overload syndrome may develop even at the recommended rate of administration, if suddenly changes the clinical condition of the patient (eg, impaired kidney function or develop infectious complications). Fat overload syndrome is characterized by hyperlipidaemia, fever, liver fatty infiltration, hepatomegaly with or without jaundice it, splenomegaly, anemia, leukopenia, thrombocytopenia, coagulation disorders, hemolysis and reticulocytosis, violation of laboratory parameters of liver function and coma. Symptoms are usually reversible and cropped at the termination of the infusion of the fat emulsion.
Introduction of large amounts of amino acids
As in the case of other amino acids solutions, exceeding the recommended medication infusion SMOFKabiven® peripheral speed, it contains amino testosterone suspension gains acids may lead to an undesirable phenomena. Perhaps the development of nausea, vomiting, chills and sweating. The infusion of amino acids may also cause a rise in body temperature. In case of violation of renal function may increase concentrations of nitrogen-containing metabolites such as creatinine and urea.
Excessive administration of dextrose
If the speed of dextrose infusion will exceed the threshold of its clearance, the patient will develop hyperglycemia.