Testosterone suspension reviews peripheral comes in bags in three sizes intended for patients with normal, moderately increased or reduced demand for nutrients. For a full parenteral nutrition may need to add vitamins, electrolytes and trace elements.

The dose should be individualized, and choice of the bag should take into account the patient’s condition, body weight and nutrient requirements.

Patients with obesity dose should be set, on the basis of ideal body weight.

The dose and drug infusion rate should be determined by the patient’s ability to metabolize fat, nitrogen and glucose, as well as his needs in energy and nutrients.

The need for nitrogen to maintain protein composition of the organism depends on the patient’s condition (ie. E. Its nutritional status and degree of catabolic stress).

The dosage regimen for adults
For patients with normal testosterone suspension reviews nutritional status or state of light catabolic stress the need for nitrogen is 0.10 – 0.15 g / kg-day (0.6 – 0.9 g / kg of d-amino acids). Patients with moderate to severe catabolic stress with impaired nutritional status or without need of 0.15 – 0.25 g / kg-day nitrogen (0.9 -1.6 g / kg day of amino acids). In some cases (such as in patients with burns or severe catabolic state) the need for nitrogen can be even higher.

The dose of 20 – 40 ml / kg day drug SMOFKabiven® corresponds peripheral 0.10 -0.20 g / kg day of nitrogen (0.6 – 1.3 g / kg day of amino acids) and 14 – 28 kcal / kg of daily energy (11 – 22 kcal / kgsut non-protein energy). This dose range covers the needs of most patients.

Infusion Rate:

The maximum infusion rate for dextrose is equal to 0.25 g / kg per hour for amino acids 0.1 g / kg per hour, and for lipids -. 0.15 g / kg per hour
maximum speed the introduction of peripheral SMOFKabiven® drug should not exceed 3.0 ml / kg per hour (this corresponds to the maximum rate of infusion of dextrose, amino acids and lipids). The recommended duration of infusion is 12-24 hours.

The maximum daily dose
maximum daily dose varies depending on the clinical condition of the patient and can change over time. The recommended maximum daily dose of 40 ml / kg / day, and provides the patient with nitrogen in an amount of 0.20 g / kg / day (corresponding to 1.3 g / kg / day of amino acids), dextrose in an amount of 2.8 g / kg / day fat in an amount of 1.1 g / kg / d and an energy of 28 kcal / kg / day (corresponding to 22 kcal / kg / day of non-protein energy).

Pediatric patients
Testosterone suspension reviews peripheral can be used in children 2 years of age.

The dose is determined by the patient’s ability to metabolize certain nutrients.

Infusion children (2 to 10 years) should start with a low dose (14-28 ml / kg / day, the dose should be increased to 10-15 ml / kg / day, the maximum dose of 40 ml / kg / day). The upper limit of the protein load in children think 4 g / kg.

In children older than 10 years can apply the same dose as in adults.

Long-term use peripheral  typically 5 to 7 days, however, can be extended up to 3-4 weeks, depending on the condition of the patient.

Precautions when using
Peripheral should be used with caution in patients with impaired fat metabolism, which may occur in patients with renal insufficiency, diabetes mellitus, pancreatitis, impaired liver function, hypothyroidism and sepsis. With the introduction of the drug in patients with peripheral such disorders need careful control of the concentration of triglycerides in the plasma and blood glucose concentrations.

Use of the drug for newborns and children up to 2 years of age is not recommended due to insufficient clinical experience.

Peripheral solutions have osmolality of 850 mOsm / l and are therefore suitable for intravenous administration in both the peripheral and the central veins. The ability to metabolize fat is individual for each patient, so the lipid metabolism of patients should be routinely monitored. Usually monitoring is reduced to a daily determination of triglycerides. The concentration of plasma triglycerides during infusion should not exceed 4 mmol / l. Lipid overdose may lead to fat overload syndrome.

This drug contains soybean oil, fish oil and egg phospholipids, which in rare cases can cause allergic reactions. Allergies to peanuts and soybeans can be cross. If there are any signs of anaphylactic reaction (such as fever, chills, rash or shortness of breath) infusion of the drug should be discontinued.

To avoid risks associated with too high a rate of infusion, it is recommended the use of volumetric infusion pump.

Disturbances of water and electrolyte balance (eg abnormally high or low levels of electrolytes in the plasma) must be corrected before the start of the infusion testosterone suspension reviewsperipheral.

Peripheral should be used with caution in patients with a tendency to delay electrolytes. In such patients, during intravenous infusion of any necessary additional control plasma electrolytes.When any pathological signs of infusion should be discontinued. Given the fact that when using central venous access increased risk of infection, you must strictly adhere to aseptic technique during CVC insertion and manipulation of the catheter.

It is necessary to monitor the concentration of glucose, electrolytes, plasma osmolarity, water balance, acid-base status and liver enzymes at least every three days.

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